MASSACHUSETTS COLLEGE OF PHARMACY AND HEALTH SCIENCES

Overview of the School:
MCPHS was founded in 1823. It is the oldest private, coeducational institution located in Boston. The Longwood Medical Area offers an educational, professional, and cultural environment and a unique opportunity for graduate study. MCPHS offers leading edge educational programs that prepare students to succeed in contemporary health practice and related professions. As a private and independent institution with a long and distinguished history, the College provides traditional and non-traditional programs of study that embody teaching excellence, active scholarly research, professional service, and strong community partnerships. MCPHS is a member of the Colleges of the Fenway, a consortium that supports the goals of working together to enhance student and faculty environments of the individual institutions while retaining the unique and special qualities of each of the schools, to gain economics benefits through collaboration, and to provide students and faculty with the opportunity to study, live, and teach in a small college environment while enjoying the resources of a major academic environment.

The Community
The College's small size encourages close relationships between students and faculty members. MCPHS, located in Boston, Massachusetts, a center of internationally renowned teaching hospitals, research centers, and universities and colleges, is an invigorating and stimulating environment in which to live and learn. Boston is a home of the arts and provides numerous cultural and social opportunities, including classical and jazz concerts, opera, ballet, museums, theaters, and professional sports; outdoor activities are abundant. Over the past three years, 80 percent of the graduates of the program have entered the pharmaceutical industry as research scientists in their respective disciplines. The remainder has gone on to medical school, post doctorate study, government research laboratories, or academia.

Programs of Study and Degree Requirements:
Through an integrated curriculum, programs of graduate study in the pharmaceutical sciences are designed on an individual basis, depending on the academic background and research interests of the student. Course work at other institutions is encouraged. Students may select their own research advisers and projects, and interdisciplinary studies may be arranged. The College offers graduate programs leading to the M.S. and Ph.D. degrees in organic/medicinal, analytical medicinal, and bio-organic chemistry, pharmaceutics/industrial pharmacy, pharmacology, and regulatory affairs and health policy. Organic/medicinal, analytical medicinal, or bio-organic chemistry offers a challenging interdisciplinary approach to study the effects of modifying the chemical structure of a drug on its biological activity or receptor affinity, to develop a method for the analysis of drugs in pharmaceutical and biological systems; to study the isolation of natural substances from plant material for potential therapeutic use; or organic synthesis of laser/fluorescent dyes. Specialization in pharmaceutics/industrial pharmacy offers a crafted balanced between theoretical foundations and practical applications to study the approaches for the development of drug delivery systems, formulation development, product development and evaluation, and the pharmacokinetics of a drug and its formulation. Pharmacology involves all facets of the effects drugs and environmental chemicals have on biological systems and their constituent parts. It includes everything from the intermolecular reactions of chemical compounds within a call to the evaluation of the effectiveness of a drug in the prevention, diagnosis, and treatment of human disease.

The M.S. program in Regulatory Affairs and Health Policy responds to the demands of the pharmaceutical and medical device industry for expertise in regulatory and health policy issues. Components, such as drug regulations, economics, business, policy development, policy analysis, and law, are explored. Candidates for this program are those interested in pursuing careers in which knowledge of the legal and regulatory environment is a prerequisite. The M.S. degree requires a minimum of 30 semester hours of credit, a thesis based on original research, and a final oral examination. The Ph.D. degree requires 50 hours of course and research credit, one skill, major and minor qualifying examinations, a dissertation based on original research, and a final oral examination.

Facilities and Resources
MCPHS was founded in 1823. The George Robert White building was constructed on the present site during 1917-18 and serves both undergraduate and graduate students. The T. Iorio Science Building provides new facilities for research and graduate instruction. The research facilities at MCPHS are well equipped for each of the areas of specialization. In addition, there are such specialized facilities as a suite for radioisotope research and a product development laboratory equipped for tableting, coating, encapsulation, and the manufacture of liquids, ointments, and sterile products. Instruments available include infrared, ultraviolet, and nuclear magnetic resonance spectrometers, gas chromatographs, and high-pressure liquid chromatographs. Computer and animal facilities are also available. In addition, research instrument facilities are available at other institutions in the Grater Boston/Cambridge area. The Sheppard Library contains approximately 40,000 volumes and receives more than 700 periodicals. Graduate students and faculty members may also use the facilities of other nearby university libraries. In addition, MCPHS has two other locations in Worcester, MA. and Manchester, NH. The Worcester campus was built in 2000 and houses the accelerated, three-year PharmD program while the Manchester location offers the 24 month graduate Physician Assistant program.

Expenses and Aid
For 2002-03, full-time tuition for graduate students ranges from $18,000 to $21,000; part-time tuition is $660 per credit. The financial aid applications consist of the Free Application for Federal Student Assistance (FAFSA). In order to be considered on time, the federal processor must receive the fully completed and signed FAFSA by March 15. Full-time graduate students receive financial assistance from the College in the form of a limited number of graduate assistantships or faculty research grants and contracts. Personal sources or other non-College sources may also be available. In 2002-2003, stipends for teaching and research assistantships begin at $11,000 for nine months and increase, depending on experience. Summer assistantships may be available. Partial tuition is remitted for full-time graduate assistants and awarded on a competitive basis according to merit and experience. Research assistantships, when available, are awarded on an individual basis. Applications for assistantships should be addressed to the Dean for Graduate Studies. New students are expected to support themselves during their first year of study. A health plan is also available at a cost to the student as the Commonwealth of Massachusetts requires all students to have a health plan. Semester college housing is not available, but apartments and rooms are available in the metropolitan Boston area and in the immediate Longwood area. Fall semester payment schedule is August 8, 2002; spring semester is December 13, 2002; and summer semester is May 7, 2003.

How to Apply/ Application
Application forms, available on request, should be received before March 1 for September admission. Students are usually matriculated in September. Candidates for graduate degrees must hold a bachelor's degree in a field acceptable to the Graduate Council. Applicants must submit a letter of intent outlining the goals for their education and their career objectives. Scores from the GRE General Test must be submitted. Students from countries in which English has not been the primary educational language must submit TOEFL scores. In addition to the general degree requirements described in the College Catalog, individual programs may establish additional requirements.

Who to Contact:
Detailed information can be obtained by contacting the address below:
Coordinator of Graduate Admissions
Massachusetts College of Pharmacy and Health Sciences
179 Longwood Avenue
Boston, MA 02115
Telephone: 617-732-2850
E-mail: admissions@mcp.edu
http://www.mcp.edu

Massachusetts College of Pharmacy and Health Sciences, Graduate Studies
The Faculty and Major Research Interests:

Timothy J. Maher, Dean of Research and Graduate Studies, Ph.D. Massachusetts College of
Pharmacy and Health Sciences

Organic/Medicinal Chemistry and Analytical Medicinal Chemistry Research Faculty

L. M. Gracz, Assistant Professor of Chemistry, Ph.D., California, Santa Barbara
Neurochemistry; membrane biophysics; molecular mechanisms of drug addition, membrane biochemistry.

C. J. Kelley, Associate Professor of Chemistry; Ph.D., Indiana
Structural characterization of natural products; organic synthesis of fluorescent dyes; indicators, laserdyes; design and organic synthesis of novel chemical agents for prevention of HIV transmission.


S. G. Kerr, Assistant Professor of Medicinal Chemistry; Ph.D., SUNY at Buffalo.
HIV and Herpes simplex enzymology and drug design; designing pro-drugs of existing anti-viral and anti-cancer agents; cyclo-oxygenase enzymes (COX 1 and 2) in neuroblastoma cells for possible roles in dementia related diseases.

A. S. Mehanna, Associate Professor of Chemistry; Ph.D., Pittsburgh
Development of cardiovascular drugs and anti-AIDS drugs.

D. A. Williams, Professor of Chemistry; Ph.D., Minnesota
Analytical methods development, drug stability, free-radical oxidation mechanisms, P450 oxidative metabolism, glucuronidation, sulfation metabolism.

Industrial Pharmacy/Pharmaceutics Research Faculty
A. A. Belmonte, Professor of Pharmaceutics; Ph.D., Connecticut
Dosage form design, transdermal drug delivery, surface and interfacial phenomena.

S. S. Jambhekar, Associate Professor of Industrial Pharmacy; Ph.D., Nebraska
Dosage forms development, cyclodextrins in dosage form development, development and evaluation of controlled release drug delivery systems, characterization and evaluation of pharmaceutical excipients; pharmacokinetics.

E. Mack, Assistant Professor of Pharmaceutics, Ph.D., Utah
Novel drug delivery systems, pharmaceutical compounding, clinical research regarding pharmacokinetics and dosage formulation, manufacturing pharmacy.

Pharmacology Research Faculty
I. Acworth, Adjunct Associate Professor of Pharmacology; D. Phil., Oxford
Neurochemistry.

B. Cohen, Professor of Pharmacology & Toxicology; Ph.D., Connecticut
Toxicology; liver-kidney injury.

L. J. Kelly, Associate Professor of Physiology; Ph.D., Johns Hopkins
Cardiovascular and pulmonary physiology.

E. Kiel, Assistant Professor of Pharmacology; Ph.D., Columbia
Regulation and function of G protein-coupled receptors, novel therapies for diabetes and obesity

D. C. Kosegarten, Professor of Pharmacology; Ph.D., Rhode Island
Cardiovascular pharmacology.

B. LeDuc, Assistant Professor of Pharmacology; Ph.D., Tufts
Drug metabolism, clinical pharmacokinetics, and pharmacogenetics.

J. W. Locke, Adjunct Associate Professor of Pharmacology; Ph.D., Emory
Behavioral and neuropharmacology.

T. J. Maher, Sawyer Professor of Pharmaceutical Sciences and Dean of Research and Graduate Studies; Ph.D., Massachusetts College of Pharmacy.
Neuropharmacology; effects of nutrients or components of nutrients (esp. amino acids) on neuronal systems using biochemical, physiological, and behavioral approaches.

M. Zdanowicz, Associate Professor of Pharmacology; Ph.D., St. Johns
Affect of growth factors IGF-1 and growth hormone on cachexia—cancer, AIDS; muscle wasting; muscle atrophy, muscular dystrophy; muscle morphology; intestinal absorption and cancer.

Drug Regulatory Affairs and Health Policy Research Faculty

D. J. Pisano, Associate Professor of Pharmacy Administration; Dean, School of Pharmacy, Worcester; and Director of Drug Regulatory Affairs and Health Policy Programs; Ph.D., Northeastern University..
Pharmacy practice and Regulatory Affairs law and regulation, professional practice dilemmas and professional liability.

J. Babiarz, Esq., Adjunct Assistant Professor of Drug Regulatory Affairs and Health Policy:
JD, Suffolk University School of Law. Law and health policy of drugs and devices.

C.Evans, Adjunct Assistant Professor of Regulatory Affairs;
PhD, University of St. Andrews (Scotland). Health Economics.

A.Grignolo, Adjunct Associate Professor of Drug Regulatory Affairs and Health Policy;
BS Duke University; PhD, University of North Carolina.

M. Hamrell, Adjunct Associate Professor of Drug Regulatory Affairs and Health Policy;
BS, University of California; PhD, University of Southern California.

D. Mantus, Adjunct Assistant Professor of Drug Regulatory Affairs and Health Policy;
BS, College of William and Mary; MS, PhD, Cornell University.

D. Pizzi, Adjunct Assistant Professor of Drug Regulatory Affairs and Health Policy;
BS, MS, Niagara University.

A.Sall, Adjunct Assistant Professor of Drug Regulatory Affairs and Health Policy;
BA, MA, Boston University.

Additional Faculty:
J. M. DeMott, Assistant Professor of Chemistry; Ph.D., Lowell
Electro analytical chemistry; electro analytical detection; biomolecules, carbohydrates and amino acids.

E. Krupat, Professor of Psychology; Ph.D., Michigan
Patient-practitioner relations or communication; patient-centered care.

R. Zackroff, Assistant Professor of Biology; Ph.D., Temple
Cytoskeleton and cell motility in ciliated protozoa; effects of anti-actin drugs on ciliated protozoa; drug adaptation and resistance mechanisms, as applied to ciliated protozoa.

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