University of Illinois at Chicago
Department of Pharmacology
Chicago, Illinois 60612

An Overview
The University of Illinois is a major research university in the Chicago area and is one of the top 50 research universities in the United States. The campus offers bachelor's degrees in ninety-eight fields, master's degrees in seventy-nine areas, and doctorates in forty-six specializations. More than 2 million volumes are housed in the University's library and its specialized collections. The University of Illinois at Chicago has been engaged in graduate and postdoctoral training programs in pharmacology since 1945 and has awarded more than 200 Ph.D. degrees. The department is represented in leading academic institutions, government agencies, and industrial settings, where many graduates hold prominent positions. The environment in the department is intellectually challenging, with multiple opportunities for interchange of ideas. The department has become a gathering place for visiting scientists in numerous disciplines and is one of the most active research environments in Chicago's scientific community.

The Community
The University of Illinois Health Sciences Center is located on an attractive campus near the Loop of Chicago. Cultural facilities such as the Chicago Symphony and Art Institute are about two miles away. The city of Chicago, the Health Sciences Center, and neighboring universities offer a challenging scientific, cultural, and intellectual atmosphere. The downtown area is a short trip by elevated train from the Health Sciences Center campus.

Nearly 30 percent of the total enrollment at UIC is at the graduate and professional level. There are approximately 30 graduate students enrolled in the Department of Pharmacology.

Programs of Study
The Department of Pharmacology offers research training in molecular and cellular pharmacology leading to the Ph.D. degree. The department, which also participates in the M.D./Ph.D. training program, ranks ninth nationally in extramural research support from the National Institutes of Health. All students are required to complete basic graduate-level courses in physiology, biochemistry, molecular biology, and pharmacology. They may then select from advanced courses offered in the department, including molecular cardiovascular pharmacology, neuropharmacology, receptor pharmacology, and vascular biology and pharmacology. Electives outside the department are also available in areas such as bioinformatics and molecular genetics.

Incoming graduate students generally complete their formal course work in the first two years. Students initiate their research during the first year. The Graduate College Preliminary Exam is given at the beginning of the third year of graduate work. Throughout this period of study, students participate in seminars, colloquia, and a variety of informal discussions. The departmental graduate student–faculty ratio is 2:1, and close tutorial relationships are emphasized.

Facilities and Resources
The departmental research facilities are generally located in the basic sciences research wing. Facilities include cell and tissue culture laboratories; freezer, cold, and warm rooms; and radioisotope rooms. Each laboratory in the department is equipped with a complete array of sophisticated instrumentation reflecting areas of specialization in molecular pharmacology. The department has laboratories available for protein sequencing and synthesis, electron microscopy, NMR spectroscopy, and mass spectroscopy; high-speed computers; and a well-supervised animal-care unit. Students in the department may use the extensive open-stack library at the Health Sciences Center and have online access to 1,500 full-text journals.

Expenses and Aid
Costs: In 2005-–06, tuition for a full program were $9550 for Illinois residents and $18,720 for nonresidents. Tuition costs are covered for those awarded fellowships and research and teaching assistantships.

Financial Aid: University fellowships and research and teaching assistantships are provided to highly qualified students. Appointments carry yearly stipends of $16,500 and provide full remission of tuition and fees.

Housing/Living Expenses: The minimum cost of living for a graduate student in Chicago is generally offset by the stipend. Students may live in on-campus apartments or dormitories or in off-campus housing of their choice.

How to Apply
Students usually begin their studies in the fall semester. While the application deadline is March 15, entering classes are usually complete by April or May, so early application is advantageous. The General Test scores of the Graduate Record Examinations are required.

Who to Contact
Committee on Graduate Studies
Department of Pharmacology
College of Medicine
University of Illinois at Chicago
835 South Wolcott Avenue (M/C 868)
Chicago, Illinois 60612



The Faculty And Their Research

  • Oscar Colamonici, Associate Professor; M.D., Uruguay, 1981. Signaling mechanisms and heterodimeric receptors such as a-interferon and the activation of the Jak-Stat pathway.
  • Xiaoping Du, Assistant Professor; M.D./Ph.D., Sydney (Australia), 1989. Signaling mechanisms of platelet and endothelial cell adhesion receptors, glycoprotein lb-IX and B integrins; regulation of integrins.
  • Ervin G. Erdos, Professor; M.D., Munich, 1950. Enzymology of peptide metabolism and its inhibitors; modes of action of the therpeutically widely used angiotensin I converting enzyme inhibitors at cellular and subcellular levels.
  • Richard D. Green, Professor; Ph.D., Minnesota, 1965. Drug-receptor interactions; receptor-effector coupling; neuromodulatory role of adenosine in striatum; development of receptor-effector systems; role of adenosine in regulating myocardial function.
  • Thomas M. Guenthner, Professor; Ph.D., Minnesota, 1975. Biotransformation of xenobiotics; toxicology; chemical carcinogenesis.
  • Tohru Kozasa, Assistant Professor; M.D./Ph.D., Tokyo, 1980. Mechanisms of signaling by heterotrimeric and small molecular weight GTP-binding proteins.
  • Stephen Chi-Tak Lam, Associate Professor; Ph.D., Toronto, 1984. Role of platelet membrane glycoproteins as receptors for adhesive proteins; signal transduction mechanisms regulating platelet adhesive functions.
  • Guy C. Le Breton, Professor; Ph.D., Chicago, 1973. Cardiovascular pharmacology: drug modulation of blood platelet function; role of calcium as intracellular transmitter; arachidonic acid metabolism.
  • Barry S. Levine, Associate Professor; D.Sc., Harvard, 1976. Toxicology and metabolism of organophosphorus insecticides; biochemical aspects of stress-toxicity interactions.
  • Isabel Lopez, Assistant Professor; Ph.D., Ohio State, 1992. Signal transduction mechanisms activated by PLCe-isoform and their role in cardiac contractivity.
  • Asrar B. Malik, Professor and Head; Ph.D., Toronto, 1971. Gene regulation in endothelial cells; expression of adhesion molecules and transcriptional regulation; physiological and pharmacological aspects of endothelial transport.
  • Richard Minshall, Assistant Professor; Ph.D., Illinois at Chicago, 1996. Role of GTPases in control of endothelial barrier function.
  • Shigehiro Nakajima, Professor; M.D., 1955, Ph.D., 1961, Tokyo. Cellular neurophysiology; electrophysiology of brain neurons in culture.
  • Miodrag Radulovacki, Professor; M.D., 1959, Ph.D., 1968, Belgrade. Role of neurotransmitters and neuromodulators (e.g., adenosine) in sleep and mechanism of action of hypnotic agents; correlative studies of behavior, EEG, and brain chemistry.
  • Randal A. Skidgel, Professor; Ph.D., California, San Diego, 1979. Role of human carboxypeptidases in activation or inactivation of peptide hormones and regulation of nitric oxide production.
    Chinnaswamy Tiruppathi, Associate Professor; Ph.D., Madras (India), 1977. Vascular endothelium and signal transduction mechanisms; albumin transcytosis; thrombin receptor activation mechanism.
    Tatyana Voyno-Yasenetskaya, Assistant Professor; M.D./Ph.D., Moscow (Russia), 1987. G-protein regulatory mechanisms and control of cellular proliferation.
  • Richard Ye, Associate Professor; M.D./Ph.D., Washington (St. Louis), 1988. Signaling and transcription regulation in phagocytic cells.
    Research Faculty
  • Viktor Brovkovych, Research Assistant Professor; Ph.D., Ukranian Academy of Science, 1988. Regulation of nitric oxide production in endothelial cells.
  • Peter A. Deddish, Research Assistant Professor; Ph.D., Northwestern, 1971. Mechanisms of processing of peptide hormones by converting enzyme (ACE), neutral endopeptidase 24.11 (NEP), kallikrein, and carboxypeptidase M.
  • Jie Fan, Research Assistant Professor; M.D., Shanghai, 1982. Transcriptional regulation of acute lung injury.
  • Panagiotis Kouklis, Research Assistant Professor; Ph.D., Heidelberg (Germany), 1990. Mechanisms of vascular injury as regulated by cell–cell adhesion molecules such as cadherins.
  • Qinghui Liu, Research Assistant Professor; Ph.D., Peking, 1992. Development of transgenic and knock-out mouse models.
  • Dolly Mehta, Research Assistant Professor; Ph.D., Delhi (India), 1989. Endothelial and smooth-muscle cell contractile mechanisms.
  • Dan Predescu, Research Assistant Professor; M.D., Ph.D., Bucharest, 1988. Regulation of endothelial barrier function by transcytosis.
  • Arshad Rahman, Research Assistant Professor; Ph.D., Aligarh (India), 1988. Recruitment of leukocytes from blood in the mediation of tissue damage and inflammation; regulation of expression of ICAM-1 and E-selectin genes.
  • Shahid Siddiqui, Research Associate Professor; Ph.D., Bombay, 1978. Role of kinesins and other molecular motors in vesicle trafficking in C. elegans.
  • Fulong Tan, Research Assistant Professor; Ph.D., Shanghai Institute of Biochemistry, Academica Sinica (China), 1982. Structure-function relationship of peptidase.
  • Stephen M. Vogel, Research Assistant Professor; Ph.D., Virginia, 1980. In vivo mechanisms of vascular injury and inflammation.
  • Nobuhiko Yokoyama, Research Assistant Professor; M.D., Ph.D., Kyushu (Japan), 1988. Signaling of neurite development.

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